Mosaburo Kainuma Selected Research

hachimijiogan (TJ 7)

1/2023	Metabolic changes in the plasma of mild Alzheimer's disease patients treated with Hachimijiogan.
1/2022	An exploratory, open-label, randomized, multicenter trial of hachimijiogan for mild Alzheimer's disease.
9/2020	The efficacy and safety of hachimijiogan for mild Alzheimer disease in an exploratory, open standard treatment controlled, randomized allocation, multicenter trial: A study protocol.
1/2017	The Traditional Japanese Herbal Medicine Hachimijiogan Elicits Neurite Outgrowth Effects in PC12 Cells and Improves Cognitive in AD Model Rats via Phosphorylation of CREB.

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Mosaburo Kainuma Research Topics

Disease

12	Chronic Hepatitis C 02/2014 - 01/2002
9	Infections 01/2021 - 10/2008
4	Cognitive Dysfunction 01/2023 - 01/2017
4	Alzheimer Disease (Alzheimer's Disease) 01/2023 - 01/2017
3	Fever (Fevers) 01/2023 - 10/2020
3	Cough 01/2023 - 10/2020
3	Dyspnea (Shortness of Breath) 01/2023 - 10/2020
3	COVID-19 01/2023 - 10/2020
3	HIV Infections (HIV Infection) 05/2014 - 11/2012
2	Fatigue 01/2023 - 10/2020
2	Liver Diseases (Liver Disease) 01/2021 - 05/2014
2	Inflammation (Inflammations) 01/2021 - 02/2012
2	Virus Diseases (Viral Diseases) 01/2021 - 02/2013
2	Edema (Dropsy) 01/2021 - 10/2016
2	Exanthema (Rash) 01/2021 - 01/2018
2	Dementia (Dementias) 10/2020 - 01/2017
2	Coinfection 05/2014 - 11/2012
2	Chronic Hepatitis B 11/2012 - 12/2011
2	Atherosclerosis 02/2012 - 02/2005
2	Viremia 12/2011 - 04/2010
2	Acquired Immunodeficiency Syndrome (AIDS) 01/2011 - 08/2009
2	Non-alcoholic Fatty Liver Disease 03/2008 - 10/2006
1	Headache (Headaches) 05/2024
1	Diarrhea 01/2023
1	Common Cold 01/2023
1	Hypesthesia (Numbness) 01/2021
1	Shock 01/2021
1	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2021
1	Hypertension (High Blood Pressure) 01/2021
1	Human Influenza (Influenza) 10/2020
1	Psychotic Disorders (Schizoaffective Disorder) 10/2020
1	Anxiety Disorders (Anxiety Disorder) 01/2017
1	Prediabetic State (Prediabetes) 06/2016
1	Persistent Infection 03/2016
1	Chronic Renal Insufficiency 02/2015
1	Carotid Artery Diseases 02/2015
1	Hemophilia A (Haemophilia) 05/2014
1	Glucose Intolerance 01/2014
1	Hyperglycemia 01/2014
1	Hip Fractures (Intertrochanteric Fractures) 06/2013
1	Osteoporosis 06/2013
1	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 01/2013
1	Brain Diseases (Brain Disorder) 01/2013
1	Escherichia coli Infections 01/2013

Drug/Important Bio-Agent (IBA)

10	InterferonsIBA 05/2014 - 01/2002
7	Ribavirin (Virazole)FDA LinkGeneric 05/2014 - 09/2010
5	RNA (Ribonucleic Acid)IBA 01/2021 - 01/2011
5	Antiviral Agents (Antivirals)IBA 05/2014 - 01/2002
4	hachimijiogan (TJ 7)IBA 01/2023 - 01/2017
4	Glucose (Dextrose)FDA LinkGeneric 06/2016 - 03/2008
3	telaprevirIBA 05/2014 - 08/2013
2	SteroidsIBA 01/2023 - 10/2020
2	Triglycerides (Triacylglycerol)IBA 02/2015 - 02/2012
2	Proteins (Proteins, Gene)FDA Link 01/2013 - 08/2009
2	NucleosidesIBA 11/2012 - 12/2011
2	CholesterolIBA 10/2006 - 02/2005
2	Mao-toIBA 06/2004 - 01/2002
1	Plant ExtractsIBA 05/2024
1	Amino Acids FDA Link 01/2023
1	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2023
1	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2022
1	TabletsIBA 01/2021
1	bu-zhong-yi-qi-tangIBA 01/2021
1	Immunosuppressive Agents (Immunosuppressants)IBA 01/2021
1	kakkon-toIBA 10/2020
1	AntipyreticsIBA 10/2020
1	shosaikotokakikyosekkoIBA 10/2020
1	Antitussive Agents (Antitussives)FDA Link 10/2020
1	Furosemide (Lasix)FDA LinkGeneric 10/2020
1	Minocycline (Cyclops)FDA LinkGeneric 01/2018
1	Amoxicillin (Wymox)FDA LinkGeneric 01/2018
1	Nerve Growth Factors (Neurotrophins)IBA 01/2017
1	Nerve Growth Factor (NGF)IBA 01/2017
1	EndostatinsIBA 06/2016
1	AlbuminsIBA 06/2016
1	Blood Coagulation Factors (Coagulation Factor)IBA 05/2014
1	Emtricitabine (Emtriva)FDA Link 05/2014
1	Tenofovir (Viread)FDA Link 05/2014
1	Raltegravir Potassium FDA Link 05/2014
1	Protease Inhibitors (Protease Inhibitor)IBA 05/2014
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2014
1	Inositol (Myoinositol)IBA 01/2014
1	Vitamin K FDA Link 06/2013
1	OsteocalcinIBA 06/2013
1	pro-brain natriuretic peptide (1-76)IBA 02/2013
1	Brain Natriuretic Peptide (Natrecor)FDA Link 02/2013
1	Anaplastic Lymphoma KinaseIBA 01/2013
1	Shiga Toxin (Shigella Toxin)IBA 01/2013
1	Prednisone (Sone)FDA LinkGeneric 01/2013
1	Vincristine (Oncovin)FDA LinkGeneric 01/2013
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2013
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2013
1	Raloxifene Hydrochloride (Evista)FDA Link 12/2012

Therapy/Procedure

9	Kampo Medicine (Kampo) 01/2023 - 01/2002
8	Therapeutics 05/2014 - 10/2008
2	Art Therapy 05/2014 - 11/2012
2	Highly Active Antiretroviral Therapy (HAART) 01/2011 - 08/2009
1	Oral Administration 01/2021
1	Artificial Respiration (Mechanical Ventilation) 01/2021
1	Drug Therapy (Chemotherapy) 01/2013